Active Recombinant Human IL10 Protein
Cat.No. : | IL10-127H |
Product Overview : | Recombinant Human IL10 Protein without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFN-£), tumor necrosis factor alpha (TNF-α), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. IL-10 also suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells. Human IL-10 can act on murine cells, while murine IL-10 is not active on human cells. |
Source : | E. coli |
Species : | Human |
Bio-activity : | MC/9 cell Proliferation, ≤5 ng/mL |
Molecular Mass : | Noncovalent Homodimer, 18.8 kDa (161 aa) |
AA Sequence : | MSPGQGTQSENSCTHFPGNLPNMLR DLRDAFSRVKTFFQMKDQLDNLLLK ESLLEDFKGYLGCQALSEMIQFYLE EVMPQAENQDPDIKAHVNSLGENLK TLRLRLRRCHRFLPCENKSKAVEQV KNAFNKLQEKGIYKAMSEFDIFINY IEAYMTMKIRN |
Endotoxin : | ≤1 EUs/μg, Kinetic LAL |
Purity : | ≥95%, Reducing and Non-Reducing SDS PAGE |
Stability : | 12 months from date of receipt when stored at -20 to -80 centigrade as supplied. 1 month when stored at 4 centigrade after reconstituting as directed. 3 months when stored at -20 to -80 centigrade after reconstituting as directed. |
Storage : | Storage Prior to Reconstitution: -20 centigrade |
Storage Buffer : | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5 |
Reconstitution : | Sterile water at 0.1 mg/mL |
Shipping : | Room temperature |
Instructions : | Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws. |
Gene Name : | IL10 interleukin 10 [ Homo sapiens (human) ] |
Official Symbol : | IL10 |
Synonyms : | IL10; interleukin 10; interleukin-10; CSIF; cytokine synthesis inhibitory factor; IL 10; IL10A; T cell growth inhibitory factor; TGIF; T-cell growth inhibitory factor; GVHDS; IL-10; MGC126450; MGC126451; |
Gene ID : | 3586 |
mRNA Refseq : | NM_000572 |
Protein Refseq : | NP_000563 |
MIM : | 124092 |
UniProt ID : | P22301 |
Products Types
◆ Recombinant Protein | ||
IL10-20R | Recombinant Rhesus monkey IL10 protein, His-tagged | +Inquiry |
IL10-2697H | Recombinant Human IL10 protein(19-178 aa), N-MBP & C-His-tagged | +Inquiry |
Il10-995M | Recombinant Mouse Il10 Protein, His-tagged | +Inquiry |
IL10-4400M | Recombinant Monkey IL10 Protein | +Inquiry |
il10-998Z | Recombinant Zebrafish il10 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL10-2079HCL | Recombinant Human IL10 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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