Active Recombinant Human IL3
Cat.No. : | IL3-200H |
Product Overview : | Recombinant human interleukin 3 expressed in CHO cells is glycosylated protein with molecular weight range from 17 to 30 kDa shown in non-reducing SDS-PAGE. |
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Description : | Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. |
Source : | CHO Cells |
Species : | Human |
Form : | Lyophilized after extensive dialysis against PBS. |
Bio-activity : | ED50< 0.1 ng/ml, measured in a cell proliferation assay using tf-1 cells, corresponding to a specific activity of>1×107 units/mg. |
Molecular Mass : | 17-30 kDa, observed by non-reducing SDS-PAGE. |
AA Sequence : | Ala20-Phe152. |
Endotoxin : | < 0.2 eu/μg, determined by lal> |
Purity : | >95% as analyzed by SDS-PAGE and HPLC. |
Storage : | Lyophilized recombinant protein remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhIL-3 should be stable up to 1 week at 4°C or up to 2 months at -20°C. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/ml. |
Gene Name : | IL3 interleukin 3 (colony-stimulating factor, multiple) [ Homo sapiens ] |
Official Symbol : | IL3 |
Synonyms : | IL3; interleukin 3 (colony-stimulating factor, multiple); interleukin-3; hematopoietic growth factor; IL 3; mast cell growth factor; MCGF; MGC79398; MGC79399; MULTI CSF; multilineage colony stimulating factor; P cell stimulating factor; mast-cell growth factor; P-cell stimulating factor; P-cell-stimulating factor; multilineage-colony-stimulating factor; multipotential colony-stimulating factor; IL-3; MULTI-CSF; |
Gene ID : | 3562 |
mRNA Refseq : | NM_000588 |
Protein Refseq : | NP_000579 |
MIM : | 147740 |
UniProt ID : | P08700 |
Chromosome Location : | 5q23-q31 |
Pathway : | Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; |
Function : | cytokine activity; growth factor activity; interleukin-3 receptor binding; |
Products Types
◆ Recombinant Protein | ||
IL3-246I | Active Recombinant Human IL3 Protein | +Inquiry |
IL3-436H | Active Recombinant Human IL3 protein(Ala20-Phe152) | +Inquiry |
IL3-167H | Active Recombinant Human IL3 Protein (Ala20-Phe152), C-His tagged, Animal-free, Carrier-free | +Inquiry |
IL3-358I | Active Recombinant Human IL3 Protein (134 aa) | +Inquiry |
IL3-455M | Active Recombinant Mouse IL3 Protein | +Inquiry |
◆ Lysates | ||
IL3-445RCL | Recombinant Rat IL3 cell lysate | +Inquiry |
IL3-607HCL | Recombinant Human IL3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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