Recombinant Human IL31 Protein, StrepII-tagged
Cat.No. : | IL31-284H |
Product Overview : | Recombinant human IL31 protein with StrepII-tag was expressed in HEK293 |
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Description : | IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. |
Source : | HEK293 |
Species : | Human |
Tag : | StrepII |
Molecular Mass : | The protein has a calculated MW of 17 kDa. |
AA Sequence : | SHTLPVRLLRPSDDVQKIVEELQSL SKMLLKDVEEEKGVLVSQNYTLPCL SPDAQPPNNIHSPAIRAYLKTIRQL DNKSVIDEIIEHLDKLIFQDAPETN ISVPTDTHECKRFILTISQQFSECM DLALKSLTSGAQQATTWSHPQFEK |
Endotoxin : | <0.1 EU/μg |
Purity : | >80% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose |
Gene Name : | IL31 interleukin 31 [ Homo sapiens (human) ] |
Official Symbol : | IL31 |
Synonyms : | IL31; interleukin 31; interleukin-31; IL 31; IL-31; |
Gene ID : | 386653 |
mRNA Refseq : | NM_001014336 |
Protein Refseq : | NP_001014358 |
MIM : | 609509 |
UniProt ID : | Q6EBC2 |
Products Types
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IL31-4514M | Recombinant Mouse IL31 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL31-172M | Recombinant Mouse IL31 Protein | +Inquiry |
IL31-05D | Recombinant Dog IL31 Protein (24-159aa) | +Inquiry |
◆ Lysates | ||
IL31-5227HCL | Recombinant Human IL31 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe IL31 may have specificity for specific diseases, with relatively few side effects being a big advantage.
IL31 activates downstream signaling pathways by binding to receptors and participates in inflammatory response and immune regulation.
It has a wide range of applications in immune inflammation, dermatology and other research fields.
Clinical studies of IL31 are ongoing, but there is no clear therapeutic effect and effectiveness assessment at this time.
IL31 research still faces many challenges, including side effect evaluation, efficacy verification and other issues, and further efforts are needed.
Optimal dose may be related to individual differences, disease type and other factors, and the appropriate dose should be determined under the guidance of a doctor when using IL31.
Customer Reviews (3)
Write a reviewIL31 product has strict quality control and complies with relevant industry standards.
It performs well in biological activity tests.
This protein has high yield and good economic benefits.
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