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Active Recombinant Human IL7

Cat.No. : IL7-9011H
Product Overview : Recombinant human IL-7 is a 17.4 kDa protein containing 153 amino acid residues. Manufactured using all non-animal reagents.
  • Specification
  • Gene Information
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Description : IL-7 is a hematopoietic growth factor, which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive.
Source : E. coli
Species : Human
Bio-activity : Determined by its ability to stimulate the proliferation of mouse 2E8 cells. The expected ED50 is ≤0.5 ng/ml, corresponding to a specific activity of ≥2 x 106 units/mg.
AA Sequence : MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH
Purity : Greater than 98% by SDS-PAGE gel and HPLC analyses.
Storage : Store at -20°C. Avoid repeated freeze-thaw cycles.
Gene Name : IL7 interleukin 7 [ Homo sapiens ]
Official Symbol : IL7
Synonyms : IL7; interleukin 7; interleukin-7; IL 7; IL-7;
Gene ID : 3574
mRNA Refseq : NM_000880
Protein Refseq : NP_000871
MIM : 146660
UniProt ID : P13232
Chromosome Location : 8q12-q13
Pathway : Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Immune System, organism-specific biosystem; Interleukin-7 signaling, organism-specific biosystem;
Function : cytokine activity; cytokine receptor binding; growth factor activity; growth factor activity; interleukin-7 receptor binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What are the application scenarios of IL7? 10/10/2020

IL7 is widely used in the research and development of immunotherapy protocols, can enhance the body's immune function, for the treatment of cancer, infection, autoimmune diseases and other diseases.

What is the mechanism of IL7 in the treatment of bladder cancer? 11/25/2019

IL7 can activate the body's immune system and enhance the immune cells' attack on bladder cancer.

What is the optimal dose of IL7 in the treatment of leukemia? 07/18/2019

The dosage of IL7 in the treatment of leukemia needs to be calculated individually according to the specific situation of the patient.

Does the efficacy of IL7 in the treatment of infectious diseases? 04/10/2019

It can enhance the function of the body's immune system, and has a certain effect on some infectious diseases.

Are there have any efficacy of IL7 in the treatment of specific cancers? 03/31/2019

Recombinant IL7 protein may have some therapeutic effect on specific cancers by activating T cells, but further clinical studies are needed.

How to prepare IL7? 03/27/2019

This is obtained by recombinant DNA technology, inserting foreign genes into the host expression system, and then through purification and other steps.

Customer Reviews (3)

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Reviews
03/27/2022

    Effective in signal transduction pathway.

    04/17/2021

      IL7 has good absorbability and high bioavailability.

      11/27/2020

        Good stability under different environmental conditions

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