Active Recombinant Human INHBB Protein
| Cat.No. : | INHBB-5119H |
| Product Overview : | Human INHBB (P09529) partial recombinant protein expressed in Hi-5 (BTI-Tn-5B1-4) cells. |
- Specification
- Gene Information
- Related Products
| Description : | The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq |
| Source : | Insect cell |
| Species : | Human |
| Form : | Lyophilized |
| Bio-activity : | The ED50 as determined by its ability to inhibit the proliferation of murine MPC-11 cells is <= 2.0 ng/mL, corresponding to a specific activity of >= 5 x 105 units/mg. |
| Molecular Mass : | 25.6 kDa |
| AA Sequence : | GLECDGRTNLCCRQQFFIDFRLIGW NDWIIAPTGYYGNYCEGSCPAYLAG VPGSASSFHTAVVNQYRMRGLNPGT VNSCCIPTKLSTMSMLYFDDEYNIV KRDVPNMIVEECGCA |
| Endotoxin : | Endotoxin level is < 0.1 ng/μg of protein (< 1 EU/μg). |
| Purity : | 95% |
| Applications : | Functional Study SDS-PAGE |
| Usage : | Activity assay SDS-PAGE The optimal working dilution should be determined by the end user. |
| Storage : | Store at -20 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : | Lyophilized from solutions contain no sodiun azide nor carrier protein |
| Gene Name : | INHBB inhibin, beta B [ Homo sapiens ] |
| Official Symbol : | INHBB |
| Synonyms : | INHBB; inhibin, beta B; inhibin, beta B (activin AB beta polypeptide); inhibin beta B chain; Inhibin, beta-2; activin beta-B chain; activin AB beta polypeptide; MGC157939; |
| Gene ID : | 3625 |
| mRNA Refseq : | NM_002193 |
| Protein Refseq : | NP_002184 |
| MIM : | 147390 |
| UniProt ID : | P09529 |
Products Types
| ◆ Lysates | ||
| INHBB-2612HCL | Recombinant Human INHBB cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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