| Description : |
The protein encoded by this gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [provided by RefSeq, Aug 2017] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
36.5 kDa |
| AA Sequence : |
MPITRMRMRPWLEMQINSNQIPGLI WINKEEMIFQIPWKHAAKHGWDINK DACLFRSWAIHTGRYKAGEKEPDPK TWKANFRCAMNSLPDIEEVKDQSRN KGSSAVRVYRMLPPLTKNQRKERKS KSSRDAKSKAKRKSCGDSSPDTFSD GLSSSTLPDDHSSYTVPGYMQDLEV EQALTPALSPCAVSSTLPDWHIPVE VVPDSTSDLYNFQVSPMPSTSEATT DEDEEGKLPEDIMKLLEQSEWQPTN VDGKGYLLNEPGVQPTSVYGDFSCK EEPEIDSPGGDIGLSLQRVFTDLKN MDATWLDSLLTPVRLPSIQAIPCAP TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
