"ITGA6" Related Products

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Recombinant Human ITGA6 Protein, MYC/DDK-tagged

Cat.No.: ITGA6-2612H
Product Overview: Recombinant Human ITGA6 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.
Source: HEK293
Species: Human
Tag : MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 117.2 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: ITGA6 integrin, alpha 6 [ Homo sapiens ]
Official Symbol: ITGA6
Synonyms: CD49f; ITGA6B; VLA-6
Gene ID: 3655
mRNA Refseq: NM_000210
Protein Refseq: NP_000201
MIM: 147556
UniProt ID: P23229

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