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Recombinant Human ITGAL Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : ITGAL-2092H
Product Overview : ITGAL MS Standard C13 and N15-labeled recombinant protein (NP_002200) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 128.77 kDa
AA Sequence : MKDSCITVMAMALLSGFFFFAPASS YNLDVRGARSFSPPRAGRHFGYRVL QVGNGVIVGAPGEGNSTGSLYQCQS GTGHCLPVTLRGSNYTSKYLGMTLA TDPTDGSILACDPGLSRTCDQNTYL SGLCYLFRQNLQGPMLQGRPGFQEC IKGNVDLVFLFDGSMSLQPDEFQKI LDFMKDVMKKLSNTSYQFAAVQFST SYKTEFDFSDYVKRKDPDALLKHVK HMLLLTNTFGAINYVATEVFREELG ARPDATKVLIIITDGEATDSGNIDA AKDIIRYIIGIGKHFQTKESQETLH KFASKPASEFVKILDTFEKLKDLFT ELQKKIYVIEGTSKQDLTSFNMELS SSGISADLSRGHAVVGAVGAKDWAG GFLDLKADLQDDTFIGNEPLTPEVR AGYLGYTVTWLPSRQKTSLLASGAP RYQHMGRVLLFQEPQGGGHWSQVQT IHGTQIGSYFGGELCGVDVDQDGET ELLLIGAPLFYGEQRGGRVFIYQRR QLGFEEVSELQGDPGYPLGRFGEAI TALTDINGDGLVDVAVGAPLEEQGA VYIFNGRHGGLSPQPSQRIEGTQVL SGIQWFGRSIHGVKDLEGDGLADVA VGAESQMIVLSSRPVVDMVTLMSFS PAEIPVHEVECSYSTSNKMKEGVNI TICFQIKSLIPQFQGRLVANLTYTL QLDGHRTRRRGLFPGGRHELRRNIA VTTSMSCTDFSFHFPVCVQDLISPI NVSLNFSLWEEEGTPRDQRAQGKDI PPILRPSLHSETWEIPFEKNCGEDK KCEANLRVSFSPARSRALRLTAFAS LSVELSLSNLEEDAYWVQLDLHFPP GLSFRKVEMLKPHSQIPVSCEELPE ESRLLSRALSCNVSSPIFKAGHSVA LQMMFNTLVNSSWGDSVELHANVTC NNEDSDLLEDNSATTIIPILYPINI LIQDQEDSTLYVSFTPKGPKIHQVK HMYQVRIQPSIHDHNIPTLEAVVGV PQPPSEGPITHQWSVQMEPPVPCHY EDLERLPDAAEPCLPGALFRCPVVF RQEILVQVIGTLELVGEIEASSMFS LCSSLSISFNSSKHFHLYGSNASLA QVVMKVDVVYEKQMLYLYVLSGIGG LLLLLLIFIVLYKVGFFKRNLKEKM EAGRGVPNGIPAEDSEQLASGQEAG DPGCLKPLHEKDSESGGGKDTRTRP LEQKLISEEDLAANDILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : ITGAL integrin subunit alpha L [ Homo sapiens (human) ]
Official Symbol : ITGAL
Synonyms : ITGAL; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); CD11A; integrin alpha-L; LFA 1; LFA-1A; LFA-1 alpha; integrin gene promoter; CD11 antigen-like family member A; lymphocyte function-associated antigen 1; leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; LFA-1; LFA1A;
Gene ID : 3683
mRNA Refseq : NM_002209
Protein Refseq : NP_002200
MIM : 153370
UniProt ID : P20701

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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