"ITGB3" Related Products

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Recombinant Human ITGB3 protein, His/S-tagged

Cat.No.: ITGB3-16H
Product Overview: Recombinant Human ITGB3(aa 20-134) fused with His/S tag was expressed in E. coli.
Description: Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands.
Source: E. coli
Species: Human
Tag : His/S
Form: Lyophilized from PBS, pH 7.4, 5% trehalose, 0.01% sarcosyl
Molecular Mass: 32.9 kDa
Purity: Greater than 95%
Storage: Store at +4 centigradefor up to 1 month, or aliquot and store at -80 centigradefor up to 12 months. Avoid repeat freeze-thaw cycles.
Reconstitution: Reconstitute in sterile PBS, pH 7.2-7.4.
Gene Name: ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) [ Homo sapiens ]
Official Symbol: ITGB3
Synonyms: ITGB3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); GP3A; integrin beta-3; CD61; GPIIIa; platelet glycoprotein IIIa; platelet membrane glycoprotein IIIa; GT; BDPLT2;
Gene ID: 3690
mRNA Refseq: NM_000212
Protein Refseq: NP_000203
UniProt ID: P05106
Chromosome Location: 17q21.32
Pathway: Arf6 signaling events, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Axon guidance, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem;
Function: cell adhesion molecule binding; identical protein binding; integrin binding; platelet-derived growth factor receptor binding; protein binding; protein disulfide isomerase activity; receptor activity; vascular endothelial growth factor receptor 2 binding; vascular endothelial growth factor receptor 2 binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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