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Active Recombinant Human KDR Protein, Strep-tagged

Cat.No. : KDR-6968H
Product Overview : Human VEGF R2 / KDR Protein, Strep Tag, Ala 20 - Glu 764 (Accession # AAI31823) was produced in human 293 cells (HEK293).
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  • Gene Information
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Source : HEK293
Species : Human
Tag : Strep
Predicted N Terminal : Ala 20
Form : Lyophilized from sterile PBS, pH7.4, 10% Trehalose.
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized Human VEGF121 at 2 μg/mL can bind Human VEGF R2, Strep Tag with a linear range of 0.01-2.5 μg/mL.
Molecular Mass : Human VEGF R2, Strep Tag is fused with twin strep tag at the C-terminus, and has a calculated MW of 86.3 kDa. The reducing (R) protein migrates as 100-110 kDa in SDS-PAGE due to glycosylation.
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >92% as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : KDR kinase insert domain receptor (a type III receptor tyrosine kinase) [ Homo sapiens ]
Official Symbol : KDR
Synonyms : KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR; VEGFR2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor;
Gene ID : 3791
mRNA Refseq : NM_002253
Protein Refseq : NP_002244
MIM : 191306
UniProt ID : P35968
Chromosome Location : 4q11-q12
Pathway : Angiogenesis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem;
Function : ATP binding; Hsp90 protein binding; growth factor binding; integrin binding; nucleotide binding; protein binding; protein tyrosine kinase activity; receptor activity; receptor signaling protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor-activated receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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