"KDR" Related Products

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Recombinant Human KDR Protein, Strep-tagged

Cat.No.: KDR-6968H
Product Overview: Human VEGF R2 / KDR Protein, Strep Tag, Ala 20 - Glu 764 (Accession # AAI31823) was produced in human 293 cells (HEK293).
Source: HEK293
Species: Human
Tag: Strep
Predicted N Terminal: Ala 20
Form: Lyophilized from sterile PBS, pH7.4, 10% Trehalose.
Bio-activity: Measured by its binding ability in a functional ELISA. Immobilized Human VEGF121 at 2 μg/mL can bind Human VEGF R2, Strep Tag with a linear range of 0.01-2.5 μg/mL.
Molecular Mass: Human VEGF R2, Strep Tag is fused with twin strep tag at the C-terminus, and has a calculated MW of 86.3 kDa. The reducing (R) protein migrates as 100-110 kDa in SDS-PAGE due to glycosylation.
Endotoxin: Less than 1.0 EU per μg by the LAL method.
Purity: >92% as determined by SDS-PAGE.
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: KDR kinase insert domain receptor (a type III receptor tyrosine kinase) [ Homo sapiens ]
Official Symbol: KDR
Synonyms: KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR; VEGFR2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor;
Gene ID: 3791
mRNA Refseq: NM_002253
Protein Refseq: NP_002244
MIM: 191306
UniProt ID: P35968
Chromosome Location: 4q11-q12
Pathway: Angiogenesis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem;
Function: ATP binding; Hsp90 protein binding; growth factor binding; integrin binding; nucleotide binding; protein binding; protein tyrosine kinase activity; receptor activity; receptor signaling protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor-activated receptor activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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