| Description : |
The protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein, which acts as a tetramer by associating with another heavy chain and two light chains, interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations-2. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
109.3 kDa |
| AA Sequence : |
MADPAECSIKVMCRFRPLNEAEILR GDKFIPKFKGDETVVIGQGKPYVFD RVLPPNTTQEQVYNACAKQIVKDVL EGYNGTIFAYGQTSSGKTHTMEGKL HDPQLMGIIPRIAHDIFDHIYSMDE NLEFHIKVSYFEIYLDKIRDLLDVS KTNLAVHEDKNRVPYVKGCTERFVS SPEEVMDVIDEGKANRHVAVTNMNE HSSRSHSIFLINIKQENVETEKKLS GKLYLVDLAGSEKVSKTGAEGAVLD EAKNINKSLSALGNVISALAEGTKT HVPYRDSKMTRILQDSLGGNCRTTI VICCSPSVFNEAETKSTLMFGQRAK TIKNTVSVNLELTAEEWKKKYEKEK EKNKTLKNVIQHLEMELNRWRNGEA VPEDEQISAKDQKNLEPCDNTPIID NIAPVVAGISTEEKEKYDEEISSLY RQLDDKDDEINQQSQLAEKLKQQML DQDELLASTRRDYEKIQEELTRLQI ENEAAKDEVKEVLQALEELAVNYDQ KSQEVEDKTRANEQLTDELAQKTTT LTTTQRELSQLQELSNHQKKRATEI LNLLLKDLGEIGGIIGTNDVKTLAD VNGVIEEEFTMARLYISKMKSEVKS LVNRSKQLESAQMDSNRKMNASERE LAACQLLISQHEAKIKSLTDYMQNM EQKRRQLEESQDSLSEELAKLRAQE KMHEVSFQDKEKEHLTRLQDAEEMK KALEQQMESHREAHQKQLSRLRDEI EEKQKIIDEIRDLNQKLQLEQEKLS SDYNKLKIEDQEREMKLEKLLLLND KREQAREDLKGLEETVSRELQTLHN LRKLFVQDLTTRVKKSVELDNDDGG GSAAQKQKISFLENNLEQLTKVHKQ LVRDNADLRCELPKLEKRLRATAER VKALESALKEAKENAMRDRKRYQQE VDRIKEAVRAKNMARRAHSAQIAKP IRPGHYPASSPTAVHAIRGGGGSSS NSTHYQKTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
