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Recombinant Human KIT Protein, His-GST-tagged

Cat.No. : KIT-1654H
Product Overview : Recombinant Human KIT isoform 2 (P10721-2) cytoplasmic domain (Thr 540-Val 972) was wxpressed in Baculovirus-Insect Cells with the N-terminal polyhistidine-tag and GST tag.
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  • Gene Information
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Source : Insect cell
Species : Human
Tag : His-GST
Form : Lyophilized Powder
Molecular Mass : The recombinant human KIT(aa 540-972) /GST chimera consists of 670 amino acids and predictes a molecular mass of 76.8 kDa. It migrates as an approximately 68 KDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : > 92 % as determined by SDS-PAGE
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage buffer : PBS, pH 7.4
Gene Name : KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog [ Homo sapiens ]
Official Symbol : KIT
Synonyms : KIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; PBT, piebald trait; mast/stem cell growth factor receptor Kit; C Kit; CD117; SCFR; p145 c-kit; proto-oncogene c-Kit; piebald trait protein; soluble KIT variant 1; tyrosine-protein kinase Kit; proto-oncogene tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; PBT; C-Kit;
Gene ID : 3815
mRNA Refseq : NM_000222
Protein Refseq : NP_000213
MIM : 164920
UniProt ID : P10721

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does KIT gene expression vary in different tissues, and what factors contribute to tissue-specific regulation? 02/13/2022

KIT expression varies across tissues due to tissue-specific transcription factors, epigenetic modifications, and microenvironmental cues influencing its regulation.

How is the expression of the KIT gene regulated at the transcriptional level? 01/14/2022

Transcription factors like PU.1 and GATA-2, along with epigenetic modifications, regulate KIT gene expression.

Contribution of KIT gene to germ cell maintenance in the testes and ovaries? 01/17/2020

KIT is crucial for germ cell survival and proliferation; mutations may lead to infertility.

What is the role of KIT gene in stem cell biology and regenerative medicine? 12/25/2019

KIT maintains and influences stem cell behavior, holding potential in regenerative medicine.

Role of KIT gene in hematopoiesis and implications in hematological disorders? 11/03/2018

KIT is vital in hematopoietic stem cell development; mutations link to leukemia and mastocytosis.

Customer Reviews (3)

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Reviews
11/28/2020

    The quality control measures are evident in the performance of this product.

    04/02/2019

      Exceptional service!

      07/19/2018

        Rapid delivery! Ordered and received the product within a short timeframe, allowing us to proceed with our experiments without delays.

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