Recombinant Human KLK3 Protein, MYC/DDK-tagged

• Cat.No.: KLK3-691H
• Product Overview: Recombinant human KLK3 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 26.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: kallikrein related peptidase 3[ Homo sapiens ]
• Official Symbol: KLK3
• Synonyms: APS; hK3; KLK2A1; PSA
• Gene ID: 354
• mRNA Refseq: NM_001648.2
• Protein Refseq: NP_001639.1
• MIM: 176820
• UniProt ID: P07288