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Recombinant Human KLK6 Protein, MYC/DDK-tagged

Cat.No. : KLK6-690H
Product Overview : Recombinant human KLK6 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
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Description : This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer's and Parkinson's disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 14.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : kallikrein related peptidase 6[ Homo sapiens ]
Official Symbol : KLK6
Synonyms : Bssp; hK6; Klk7; PRSS18; PRSS9; SP59
Gene ID : 5653
mRNA Refseq : NM_001012964.1
Protein Refseq : NP_001012982.1
MIM : 602652
UniProt ID : Q92876

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the association between Klk6 recombinant protein and tumors? 09/07/2022

Studies have shown that Klk6 recombinant protein may be involved in the occurrence and progression of tumors, especially in pancreatic and gastric cancers.

What is the status of Klk6 recombinant protein in pregnant women? 07/07/2022

The level of Klk6 recombinant protein in pregnant women may change due to the needs of fetal growth and development, and regular monitoring is required.

What are the treatments for Klk6 recombinant protein? 01/08/2022

The current treatments for Klk6 recombinant protein mainly include gene therapy, protein replacement therapy, and drug therapy for trypsin activity.

Is Klk6 recombinant protein associated with other systemic diseases? 06/19/2021

Studies have shown that Klk6 recombinant protein may be associated with cardiovascular diseases, liver diseases, and lung diseases.

Does the Klk6 recombinant protein have a role in humans? 09/26/2020

Klk6 recombinant protein is mainly involved in the digestive process in the human body, helping to break down proteins in food.

If the level of Klk6 recombinant protein is abnormal, what should I do? 05/15/2020

If the level of Klk6 recombinant protein is abnormal, the treatment may include the use of drugs or other special treatments, depending on the condition and the doctor's recommendation.

Customer Reviews (3)

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Reviews
06/15/2023

    When experimenting with the KLK6, clear and consistent results are available for easy data analysis and interpretation.

    02/15/2023

      KLKKLK6 products are available in a wide range of specifications for experimental designs of different sizes and needs.

      04/19/2021

        KLK6 has a long half-life and is able to maintain stability and reliability during experiments.

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