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Recombinant Human KLK7 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : KLK7-889H
Product Overview : KLK7 MS Standard C13 and N15-labeled recombinant protein (NP_005037) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 27.6 kDa
AA Sequence : MARSLLLPLQILLLSLALETAGEEA QGDKIIDGAPCARGSHPWQVALLSG NQLHCGGVLVNERWVLTAAHCKMNE YTVHLGSDTLGDRRAQRIKASKSFR HPGYSTQTHVNDLMLVKLNSQARLS SMVKKVRLPSRCEPPGTTCTVSGWG TTTSPDVTFPSDLMCVDVKLISPQD CTKVYKDLLENSMLCAGIPDSKKNA CNGDSGGPLVCRGTLQGLVSWGTFP WGQPNDPGVYTQVCKFTKWINDTMK KHRTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : KLK7 kallikrein-related peptidase 7 [ Homo sapiens (human) ]
Official Symbol : KLK7
Synonyms : KLK7; kallikrein-related peptidase 7; kallikrein 7 (chymotryptic, stratum corneum), PRSS6; kallikrein-7; SCCE; signal protein; serine protease 6; stratum corneum chymotryptic enzyme; kallikrein 7 (chymotryptic, stratum corneum); hK7; PRSS6;
Gene ID : 5650
mRNA Refseq : NM_005046
Protein Refseq : NP_005037
MIM : 604438
UniProt ID : P49862

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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