Recombinant Human KNG1 (LMW) protein, His-tagged
Cat.No. : | KNG1-375H |
Product Overview : | Recombinant Human KNG1 protein (Gln19-Ser427), fused to His tag at C-terminus, was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Kininogen-1 (KNG1) is also known as HMWK, BDK, KNG, is a secreted protein which contains three cystatin domains. KNG1 can be cleaved into the following six chains: Kininogen-1 heavy chain, T-kinin, Bradykinin, Lysyl-bradykinin, Kininogen-1 light chain, Low molecular weight growth-promoting factor. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. LMW-kininogen inhibits the aggregation of thrombocytes; LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 um filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 46.6 kDa. The protein migrates as 50-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | 409 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >92% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | KNG1 |
Official Symbol : | KNG1 |
Synonyms : | KNG1; kininogen 1; BDK, kininogen , KNG; kininogen-1; alpha 2 thiol proteinase inhibitor; bradykinin; HMWK; fitzgerald factor; high molecular weight kininogen; alpha-2-thiol proteinase inhibitor; williams-Fitzgerald-Flaujeac factor; BDK; KNG |
Gene ID : | 3827 |
mRNA Refseq : | NM_000893 |
Protein Refseq : | NP_000884 |
MIM : | 612358 |
UniProt ID : | P01042 |
Products Types
◆ Recombinant Protein | ||
KNG1-687H | Recombinant Human KNG1 Protein, MYC/DDK-tagged | +Inquiry |
Kng1-4893M | Recombinant Mouse Kng1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Kng1-3300M | Active Recombinant Mouse Kng1 protein(Glu21-Ser480), His-tagged | +Inquiry |
KNG1-60H | Recombinant Human KNG1 Protein, DYKDDDDK-tagged | +Inquiry |
KNG1-820H | Recombinant Human KNG1 Protein | +Inquiry |
◆ Native Protein | ||
KNG1-29338TH | Native Human KNG1 | +Inquiry |
KNG1-1844H | Native Human Kininogen 1 | +Inquiry |
KNG1-29146TH | Native Human KNG1 | +Inquiry |
◆ Lysates | ||
KNG1-2284HCL | Recombinant Human KNG1 cell lysate | +Inquiry |
KNG1-2276MCL | Recombinant Mouse KNG1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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