Recombinant Human KNG1 Protein, MYC/DDK-tagged
Cat.No. : | KNG1-687H |
Product Overview : | Recombinant human KNG1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
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Description : | (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting. [UniProtKB/Swiss-Prot Function] |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 47.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | kininogen 1[ Homo sapiens ] |
Official Symbol : | KNG1 |
Synonyms : | BDK; BK; KNG |
Gene ID : | 3827 |
mRNA Refseq : | NM_000893.3 |
Protein Refseq : | NP_000884.1 |
MIM : | 612358 |
UniProt ID : | P01042 |
Products Types
◆ Recombinant Protein | ||
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Kng1-4893M | Recombinant Mouse Kng1 Protein, His (Fc)-Avi-tagged | +Inquiry |
KNG1-60H | Recombinant Human KNG1 Protein, DYKDDDDK-tagged | +Inquiry |
KNG1-4902H | Recombinant Human KNG1 Protein, GST-tagged | +Inquiry |
◆ Native Protein | ||
KNG1-1844H | Native Human Kininogen 1 | +Inquiry |
KNG1-29338TH | Native Human KNG1 | +Inquiry |
KNG1-18H | Native Human Kininogen, LMW | +Inquiry |
◆ Lysates | ||
KNG1-2276MCL | Recombinant Mouse KNG1 cell lysate | +Inquiry |
KNG1-2284HCL | Recombinant Human KNG1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Write a reviewUtilizing protein reagents reduces material consumption in experiments, resulting in resource conservation.
The usage method of protein reagents is flexible, adapting to various experimental requirements.
The precise and reliable results achieved by employing protein reagents make them highly favored in scientific research.
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