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Active Recombinant Human KRAS Protein, His-tagged

Cat.No. : KRAS-3489H
Product Overview : Recombinant human KRAS (2-186) was expressed in E.coli cells using an N-terminal His tag.
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  • Gene Information
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Description : This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Source : E. coli
Species : Human
Tag : His
Form : Liquid
Bio-activity : 3nmol/min/mg
Molecular Mass : 23 kDa
Purity : >90%
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Concentration : 0.1μg/μl
Storage buffer : 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Gene Name : KRAS KRAS proto-oncogene, GTPase [ Homo sapiens (human) ]
Official Symbol : KRAS
Synonyms : NS; NS3; CFC2; RALD; K-Ras; KRAS1; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; c-Ki-ras2
Gene ID : 3845
mRNA Refseq : NM_033360
Protein Refseq : NP_203524.1
MIM : 190070
UniProt ID : P01116

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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