Recombinant Human L2HGDH Protein, MYC/DDK-tagged

• Cat.No.: L2HGDH-173H
• Product Overview: Recombinant human L2HGDH protein, fused to MYC/DDK-tag at C-terminal, was expressed in HEK293.

Specification

• Description: This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation. [provided by RefSeq, Jul 2008].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 45.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: L-2-hydroxyglutarate dehydrogenase [ Homo sapiens ]
• Official Symbol: L2HGDH
• Synonyms: C14orf160; L2HGA
• Gene ID: 79944
• mRNA Refseq: NM_024884.2
• Protein Refseq: NP_079160.1
• MIM: 609584
• UniProt ID: Q9H9P8