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Active Recombinant Human LAG3 protein(Met1-Leu450), mFc-tagged

Cat.No. : LAG3-15H
Product Overview : Recombinant Human LAG3 (NP_002277.4) (Met1-Leu450) was expressed in HEK293 with the Fc region of Mouse IgG1 at the C-terminus.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : C-mFc
Protein length : Met1-Leu450
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : Immobilized LAG3 Protein, Human, Recombinant (ECD, mFc Tag) at 2 μg/mL (100 μL/well) can bind Anti-LAG3(BMS)-IgG4 Antibody (Relatlimab), the EC50 is 8-40 ng/mL.
Molecular Mass : The recombinant human LAG3 consists of 662 amino acids and predicts a molecular mass of 72.6 kDa. As a result of glycosylation, it migRates as an approximately 87.3 KDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 90 % as determined by SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : LAG3 lymphocyte-activation gene 3 [ Homo sapiens ]
Official Symbol : LAG3
Synonyms : LAG3; lymphocyte-activation gene 3; lymphocyte activation gene 3 protein; CD223;
Gene ID : 3902
mRNA Refseq : NM_002286
Protein Refseq : NP_002277
MIM : 153337
UniProt ID : P18627

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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