Recombinant Human LAIR1 Protein, MYC/DDK-tagged

• Cat.No.: LAIR1-166H
• Product Overview: Recombinant human LAIR1 protein, fused to MYC/DDK-tag at C-terminal, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 31.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: leukocyte associated immunoglobulin like receptor 1 [ Homo sapiens ]
• Official Symbol: LAIR1
• Synonyms: CD305; LAIR-1
• Gene ID: 3903
• mRNA Refseq: NM_002287.3
• Protein Refseq: NP_002278.1
• MIM: 602992
• UniProt ID: Q6GTX8