Recombinant Human MAD2L2 Protein, MYC/DDK-tagged

• Cat.No.: MAD2L2-685H
• Product Overview: Recombinant Human MAD2L2, transcript variant 1, fused with MYC/DDK tag at the C-terminus was produced in HEK293.

Specification

• Description: The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 24.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) [ Homo sapiens ]
• Official Symbol: MAD2L2
• Synonyms: MAD2L2; MAD2 mitotic arrest deficient-like 2 (yeast); MAD2 (mitotic arrest deficient, yeast, homolog) like 2; mitotic spindle assembly checkpoint protein MAD2B; MAD2B; mitotic arrest deficient homolog like 2; REV7; hREV7; REV7 homolog; MAD2-like protein 2; mitotic arrest deficient homolog-like 2; mitotic arrest deficient 2-like protein 2; MAD2 (mitotic arrest deficient, yeast, homolog)-like 2
• Gene ID: 10459
• mRNA Refseq: NM_001127325
• Protein Refseq: NP_001120797
• MIM: 604094
• UniProt ID: Q9UI95