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Recombinant Human METTL3/METTL14 complex Protein, GST-tagged

Cat.No. : METTL3-043H
Product Overview : Full-length recombinant human METTL3/METTL14 complex was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
Source : Insect Cell
Species : Human
Tag : GST
Molecular Mass : 100 kDa (METTL3) and 84 kDa (METTL14)
Purity : > 90%
Applications : Activity Assay
Stability : One year at -70 centigrade from date of shipment.
Storage : Store product at –70 centigrade. For optimal storage, aliquot targets into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 μg/μL
Storage Buffer : Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM Glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Shipping : Dry ice
Gene Name : METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit [ Homo sapiens (human) ]
Official Symbol : METTL3
Synonyms : METTL3; methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit; M6A; IME4; Spo8; MT-A70; hMETTL3; N6-adenosine-methyltransferase catalytic subunit; N6-adenosine-methyltransferase 70 kDa subunit; adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase; mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase; mRNA m(6)A methyltransferase; methyltransferase like 3; methyltransferase-like protein 3; EC 2.1.1.348
Gene ID : ?term=56339
mRNA Refseq : NM_019852
Protein Refseq : NP_062826
MIM : 612472
UniProt ID : Q86U44

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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04/16/2023

    Its reliability, versatility, and ability to deliver clear and reliable results make it a top choice for researchers in need of a high-quality protein for their experiments.

    04/14/2020

      This enhanced visibility and distinctness of the protein bands greatly aided in the accurate analysis and interpretation of my Western Blotting results.

      01/03/2020

        METTL3 protein has exhibited remarkable performance in Western Blotting experiments.

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