Recombinant Human MFGE8 Protein, MYC/DDK-tagged
Cat.No. : | MFGE8-1242H |
Product Overview : | Recombinant human MFGE8 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 42.9 kDa |
Purity : | >50 ug/mL as determined by microplate BCA method |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | MFGE8 milk fat globule-EGF factor 8 protein [ Homo sapiens ] |
Official Symbol : | MFGE8 |
Synonyms : | BA46; EDIL1; HMFG; hP47; HsT19888; MFG-E8; MFGM; OAcGD3S; SED1; SPAG10 |
Gene ID : | 4240 |
mRNA Refseq : | NM_001114614 |
Protein Refseq : | NP_001108086 |
MIM : | 602281 |
UniProt ID : | Q08431 |
Products Types
◆ Recombinant Protein | ||
MFGE8-4385H | Recombinant Human MFGE8 Protein, GST-tagged | +Inquiry |
MFGE8-3466H | Recombinant Human MFGE8 Protein, His (Fc)-Avi-tagged | +Inquiry |
MFGE8-220H | Recombinant Human MFGE8 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
MFGE8-445H | Recombinant Human MFGE8 Protein (Met1-Cys387), His-AVI-tagged, Biotinylated | +Inquiry |
MFGE8-652H | Recombinant Human MFGE8 Protein (24-387 aa), His-SUMO-tagged | +Inquiry |
◆ Native Protein | ||
MFGE8-8518B | Native Bovine MFGE8, Fluoresence-labeled | +Inquiry |
MFGE8-288B | Native Bovine Lactadherin | +Inquiry |
MFGE8-289B | Native MFG-E8 | +Inquiry |
◆ Lysates | ||
MFGE8-422HCL | Recombinant Human MFGE8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThe structure of MFGE8 determines its ability and stability to bind to other proteins. The study of its structure can help us understand its function and mechanism of action.
MFGE8 can interact with a variety of other proteins, including Caspase-3, Caspase-8, EGFR, etc. These interactions enable it to regulate processes such as apoptosis, signal transduction, and cell adhesion.
Future studies of MFGE8 may focus on the following aspects: its structure-function relationship, mechanisms of interaction with other proteins, regulatory mechanisms in cells, and potential therapeutic applications. At the same time, the study of MFGE8's interaction with specific signal transduction pathways and its regulatory effect on cell growth and differentiation will also become one of the future research priorities.
Therapeutic strategies for MFGE8 may include regulating its expression level, inhibiting its interaction with other proteins, and promoting or inhibiting its function. These methods may have potential applications in the treatment of cancer, neurodegenerative diseases, and autoimmune diseases.
In neurodegenerative diseases, MFGE8 may influence the survival and death processes of neurons by regulating apoptosis and signal transduction. It could be a potential target for the treatment of neurodegenerative diseases.
Drug development against MFGE8 needs to consider its specificity, safety, pharmacokinetic properties, and potential side effects. In addition, issues such as the dosage form, route of administration and design of clinical trials need to be considered.
Customer Reviews (3)
Write a reviewIt has high application effect and safety in clinical treatment.
MFGE8 has a high resolution in Western blots, which can distinguish similar protein molecular weights.
Good stability and activity retention during long-term storage.
Ask a Question for All MFGE8 Products
Required fields are marked with *
My Review for All MFGE8 Products
Required fields are marked with *
Inquiry Basket