Active Recombinant Human MIF Protein, His-tagged
Cat.No. : | MIF-736H |
Product Overview : | Recombinant Human MIF fused with His tag at N-terminal was expressed in Hi-5 Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. |
Source : | Hi-5 Insect cells |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer, 100mM NaCl, pH 7.2 |
Bio-activity : | Determined by its ability to inhibit monocyte migration. |
Molecular Mass : | 15 kDa |
AA Sequence : | HHHHHHHHAMPMFIVNTNVPRASVP DGFLSELTQQLAQATGKPPQYIAVH VVPDQLMAFGGSSEPCALCSLHSIG KIGGAQNRSYSKLLCGLLAERLRIS PDRVYINYYDMNAANVGWNNSTFA |
Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Resuspend the protein in the desired concentration in proper buffer |
Gene Name : | MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) [ Homo sapiens ] |
Official Symbol : | MIF |
Synonyms : | MIF; macrophage migration inhibitory factor (glycosylation-inhibiting factor); GLIF; macrophage migration inhibitory factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase; phenylpyruvate tautomerase; MMIF; |
Gene ID : | 4282 |
mRNA Refseq : | NM_002415 |
Protein Refseq : | NP_002406 |
MIM : | 153620 |
UniProt ID : | P14174 |
Products Types
◆ Recombinant Protein | ||
MIF-2445H | Recombinant Human MIF Protein, His-tagged | +Inquiry |
MIF-2593R | Recombinant Rhesus Macaque MIF Protein, His (Fc)-Avi-tagged | +Inquiry |
MIF-332M | Recombinant Human MIF Protein (115 aa) | +Inquiry |
MIF-208H | Recombinant Human MIF Protein | +Inquiry |
MIF-2444H | Recombinant Human MIF Protein, His-tagged | +Inquiry |
◆ Lysates | ||
MIF-1884MCL | Recombinant Mouse MIF cell lysate | +Inquiry |
MIF-1917HCL | Recombinant Human MIF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (5)
Ask a questionMIF can promote inflammation and immune responses, contributing to autoimmune diseases like rheumatoid arthritis and systemic lupus erythematosus.
MIF is involved in the regulation of neuroinflammation and has implications in neurodegenerative diseases like Alzheimer's.
MIF is implicated in conditions like autoimmune diseases, sepsis, and cancer.
Yes, targeting MIF with drugs or antibodies is being explored as a potential treatment for autoimmune diseases.
MIF is also studied in the context of cardiovascular diseases, neuroinflammation, and wound healing.
Customer Reviews (3)
Write a reviewThe cost-effectiveness of the MIF protein, competitive pricing, and the availability of bulk purchase options provided by the manufacturer also align with my budget considerations, allowing me to optimize my resources.
the manufacturer's commitment to delivering the MIF protein in a timely manner is greatly appreciated.
the excellent technical support provided by the manufacturer is of immense value to me.
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