Active Recombinant Human MMP7 protein

• Cat.No.: MMP7-22H
• Product Overview: Recombinant Human MMP7 protein catalytic domain (Tyr95-Lys267), fused to a C-terminal purification tag, was expressed in E.coli and purified by multi-step chromatography.

Specification

• Source: E.coli
• Species: Human
• Form: Liquid. In 50mM TRIS, 5mM CaCl2, 300mM NaCl, 20µM ZnCl2, 0.5% Brij-35, and 30% glycerol.
• Bio-activity: Activity: Preincubation of MMP-7 catalytic domain at 19nM with the broad-spectrum inhibitor GM6001 at 100nM for 1 hour completely inhibits enzymatic activity; Specific Activity: ≥16 U/µg. One U=100 pmol/min at 37 centigrade using the colorimetric thiopeptolide Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt (100 µM) as substrate.
• Molecular Mass: 20.4 kDa
• Protein length: 173
• Purity: ≥95% (SDS-PAGE)
• Applications: Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors.
• Storage: Long Term Storage: -80 centigrade.

Gene Information

• Gene Name: MMP7
• Official Symbol: MMP7
• Synonyms: MMP-7; MPSL1; PUMP-1; Matrix metalloproteinase 7; Matrilysin; Pump
• Gene ID: 4316
• mRNA Refseq: NM_002423.5
• Protein Refseq: NP_002414.1
• MIM: 178990
• UniProt ID: P09237