Recombinant Human MTAP Protein, MYC/DDK-tagged
Cat.No. : | MTAP-2005H |
Product Overview : | Recombinant human MTAP protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293 |
- Specification
- Gene Information
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Description : | This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq, Jul 2008]. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 31.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | MTAP methylthioadenosine phosphorylase [ Homo sapiens ] |
Official Symbol : | MTAP |
Synonyms : | BDMF; c86fus; DMSFH; DMSMFH; HEL-249; LGMBF; MSAP |
Gene ID : | 4507 |
mRNA Refseq : | NM_002451 |
Protein Refseq : | NP_002442 |
MIM : | 156540 |
UniProt ID : | Q13126 |
Products Types
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◆ Lysates | ||
MTAP-424HCL | Recombinant Human MTAP lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, the presence or absence of MTAP is being investigated as a potential predictive biomarker for the response to specific anticancer therapies.
Yes, molecular diagnostic techniques can assess MTAP status in tumors, aiding in cancer diagnosis and prognosis.
One challenge is the development of targeted therapies that selectively exploit MTAP deficiency without causing significant side effects in normal cells.
Researchers are exploring targeted therapies that exploit MTAP deficiency in cancer cells, aiming for more effective and selective treatments.
MTAP-deficient cells may be more sensitive to certain chemotherapeutic agents, offering a potential therapeutic advantage in cancer treatment.
Customer Reviews (3)
Write a reviewWhat sets the MTAP protein apart is not only its outstanding quality but also the excellent technical support provided by the manufacturer.
the MTAP protein's versatility extends beyond its proven usefulness in in vitro experiments.
Whether studying angiopoietin signaling pathways, vascular remodeling, or endothelial cell biology, the MTAP protein is an invaluable tool for researchers.
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