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Recombinant Human MYL12A Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : MYL12A-4844H
Product Overview : MYL12A MS Standard C13 and N15-labeled recombinant protein (NP_006462) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 19.8 kDa
AA Sequence : MSSKRTKTKTKKRPQRATSNVFAMF DQSQIQEFKEAFNMIDQNRDGFIDK EDLHDMLASLGKNPTDEYLDAMMNE APGPINFTMFLTMFGEKLNGTDPED VIRNAFACFDEEATGTIQEDYLREL LTTMGDRFTDEEVDELYREAPIDKK GNFNYIEFTRILKHGAKDKDDTRTR PLEQKLISEEDLAANDILDYKDDDD KV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : MYL12A myosin light chain 12A [ Homo sapiens (human) ]
Official Symbol : MYL12A
Synonyms : MYL12A; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light polypeptide, regulatory, non sarcomeric (20kD); myosin regulatory light chain 12A; MLCB; MRCL3; MRLC3; MYL2B; myosin regulatory light chain 3; MLC-2B; myosin RLC; myosin regulatory light chain MRCL3; myosin regulatory light chain MRLC3; myosin regulatory light chain 2, nonsarcomeric; myosin, light polypeptide, regulatory, non-sarcomeric (20kD);
Gene ID : 10627
mRNA Refseq : NM_006471
Protein Refseq : NP_006462
UniProt ID : P19105

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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