Recombinant Human NEFL protein, MYC/DDK-tagged NEFL-13H

Recombinant Human NEFL protein, MYC/DDK-tagged

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Recombinant Human NEFL protein, MYC/DDK-tagged

NEFL Related Products

Bovine(1)
Human(9)
Mouse(4)
Rat(2)
Rhesus Macaque(1)

GST(1)
His(8)
His|SUMO|Myc(1)
Myc/DDK(3)
Myc|DDK(1)
N/A(3)

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Specification Gene Information Related Products

Cat.No. :	NEFL-13H
Product Overview :	Recombinant Human NEFL fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description :	Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Source :	HEK293
Species :	Human
Tag :	MYC/DDK
Form :	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass :	61.3 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Quality Control Test :	54.5 kDa
Notes :	Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Concentration :	>50 ug/mL as determined by microplate BCA method
Figure :

Gene Name :	NEFL neurofilament, light polypeptide [ Homo sapiens ]
Official Symbol :	NEFL
Synonyms :	NEFL; neurofilament, light polypeptide; neurofilament, light polypeptide 68kDa; neurofilament light polypeptide; CMT1F; CMT2E; NF68; NFL; neurofilament subunit NF-L; neurofilament triplet L protein; neurofilament protein, light chain; light molecular weight neurofilament protein; NF-L; FLJ53642;
Gene ID :	4747
mRNA Refseq :	NM_006158
Protein Refseq :	NP_006149
MIM :	162280
UniProt ID :	P07196
Chromosome Location :	8p21.2
Pathway :	Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; CREB phosphorylation through the activation of CaMKII, organism-specific biosystem; CREB phosphorylation through the activation of Ras, organism-specific biosystem; Neuronal System, organism-specific biosystem; Neurotransmitter Receptor Binding And Downstream Transmission In ThePostsynaptic Cell, organism-specific biosystem;
Function :	identical protein binding; protein C-terminus binding; protein binding; structural constituent of cytoskeleton;

Products Types

◆ Recombinant Protein

NEFL-10563M

Recombinant Mouse Nefl Protein, Myc/DDK-tagged

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NEFL-23H

Recombinant Human NEFL Protein, His-tagged

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NEFL-1472M

Recombinant Mouse NEFL Protein (2-543 aa), His-tagged

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NEFL-1292H

Recombinant Human NEFL Protein, His-SUMO/MYC-tagged

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Nefl-4363M

Recombinant Mouse Nefl Protein, Myc/DDK-tagged

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◆ Native Protein

NEFL-181B

Native bovine NEFL

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◆ Lysates

NEFL-3884HCL

Recombinant Human NEFL 293 Cell Lysate

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Related Gene

NEFL

Datasheet MSDS

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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