Active Recombinant Human NRG1 Protein, His-tagged
| Cat.No. : | NRG1-01H |
| Product Overview : | Recombinant human NRG1 (20-241aa), fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatographytechniques. |
- Specification
- Gene Information
- Related Products
| Description : | The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). |
| Source : | Insects cells |
| Species : | Human |
| Tag : | His |
| Form : | Liquid |
| Bio-activity : | Measured in a cell proliferation assay using MCF7 human breast cancer cell. The ED50 range ≤ 15 ng/mL. |
| Molecular Mass : | 25.1kDa(231aa) |
| AA Sequence : | |
| Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
| Purity : | > 90% by SDS-PAGE |
| Applications : | SDS-PAGE, Bioactivity |
| Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : | 0.5 mg/mL (determined by Absorbance at 280nm) |
| Storage Buffer : | In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
| Gene Name : | NRG1 neuregulin 1 [ Homo sapiens (human) ] |
| Official Symbol : | NRG1 |
| Synonyms : | NRG1; neuregulin 1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; pro-neuregulin-1, membrane-bound isoform; acetylcholine receptor-inducing activity; glial growth factor 2; heregulin, alpha (45kD, ERBB2 p185-activator); neu differentiation factor; pro-NRG1; sensory and motor neuron derived factor |
| Gene ID : | 3084 |
| mRNA Refseq : | NM_013958 |
| Protein Refseq : | NP_039252 |
| MIM : | 142445 |
| UniProt ID : | Q02297 |
Products Types
| ◆ Lysates | ||
| NRG1-1591HCL | Recombinant Human NRG1 cell lysate | +Inquiry |
| NRG1-001CCL | Recombinant Canine NRG1 cell lysate | +Inquiry |
| NRG1-1592HCL | Recombinant Human NRG1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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