Active Recombinant Human NRTN Protein
| Cat.No. : | NRTN-750H |
| Product Overview : | Recombinant Human NRTN was expressed in E. coli. |
- Specification
- Gene Information
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| Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. |
| Source : | E. coli |
| Species : | Human |
| Form : | Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer, 100mM NaCl, pH 7.2 |
| Bio-activity : | Human Neurturin at a concentration of 100 ng/ml will support the survival of 65% of newborn rat sympathetic neurons. |
| Molecular Mass : | 11.8 kDa |
| AA Sequence : | ARLGARPCGLRELEVRVSELGLGYA SDETVLFRYCAGACEAAARVYDLGL RRLRQRRRLRRERVRAQPCCRPTAY EDEVSFLDAHSRYHTVHELSARECA CV |
| Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
| Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : | Resuspend the protein in the desired concentration in proper buffer |
| Gene Name : | NRTN neurturin [ Homo sapiens ] |
| Official Symbol : | NRTN |
| Synonyms : | NRTN; neurturin; NTN; |
| Gene ID : | 4902 |
| mRNA Refseq : | NM_004558 |
| Protein Refseq : | NP_004549 |
| MIM : | 602018 |
| UniProt ID : | Q99748 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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