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Recombinant Human NTRK3 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : NTRK3-2936H
Product Overview : NTRK3 MS Standard C13 and N15-labeled recombinant protein (NP_002521) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 92.8 kDa
AA Sequence : MDVSLCPAKCSFWRIFLLGSVWLDY VGSVLACPANCVCSKTEINCRRPDD GNLFPLLEGQDSGNSNGNASINITD ISRNITSIHIENWRSLHTLNAVDME LYTGLQKLTIKNSGLRSIQPRAFAK NPHLRYINLSSNRLTTLSWQLFQTL SLRELQLEQNFFNCSCDIRWMQLWQ EQGEAKLNSQNLYCINADGSQLPLF RMNISQCDLPEISVSHVNLTVREGD NAVITCNGSGSPLPDVDWIVTGLQS INTHQTNLNWTNVHAINLTLVNVTS EDNGFTLTCIAENVVGMSNASVALT VYYPPRVVSLEEPELRLEHCIEFVV RGNPPPTLHWLHNGQPLRESKIIHV EYYQEGEISEGCLLFNKPTHYNNGN YTLIAKNPLGTANQTINGHFLKEPF PESTDNFILFDEVSPTPPITVTHKP EEDTFGVSIAVGLAAFACVLLVVLF VMINKYGRRSKFGMKGPVAVISGEE DSASPLHHINHGITTPSSLDAGPDT VVIGMTRIPVIENPQYFRQGHNCHK PDTYVQHIKRRDIVLKRELGEGAFG KVFLAECYNLSPTKDKMLVAVKALK DPTLAARKDFQREAELLTNLQHEHI VKFYGVCGDGDPLIMVFEYMKHGDL NKFLRAHGPDAMILVDGQPRQAKGE LGLSQMLHIASQIASGMVYLASQHF VHRDLATRNCLVGANLLVKIGDFGM SRDVYSTDYYRVGGHTMLPIRWMPP ESIMYRKFTTESDVWSFGVILWEIF TYGKQPWFQLSNTEVIECITQGRVL ERPRVCPKEVYDVMLGCWQREPQQR LNIKEIYKILHALGKATPIYLDILG TRTRPLEQKLISEEDLAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : NTRK3 neurotrophic receptor tyrosine kinase 3 [ Homo sapiens (human) ]
Official Symbol : NTRK3
Synonyms : NTRK3; neurotrophic tyrosine kinase, receptor, type 3; NT-3 growth factor receptor; TRKC; GP145-TrkC; ETV6-NTRK3 fusion; tyrosine kinase receptor C; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; gp145(trkC);
Gene ID : 4916
mRNA Refseq : NM_002530
Protein Refseq : NP_002521
MIM : 191316
UniProt ID : Q16288

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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