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Recombinant Human OLIG2 protein, T7/His-tagged

Cat.No. : OLIG2-185H
Product Overview : Recombinant human Olig2 cDNA (323 aa) fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Human
Tag : T7/His
Form : 0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol.
AA Sequence : MASMTGGQQMGRGHHHHHHGNLYFQ GGEFDSDASLVSSRPSSPEPDDLFL PARSKGSSGSAFTGGTVSSSTPSDC PPELSAELRGAMGSAGAHPGDKLGG SGFKSSSSSTSSSTSSAAASSTKKD KKQMTEPELQQLRLKINSRERKRMH DLNIAMDGLREVMPYAHGPSVRKLS KIATLLLARNYILMLTNSLEEMKRL VSEIYGGHHAGFHPSACGGLAHSAP LPAATAHPAAAAHAAHHPAVHHPIL PPAAAAAAAAAAAAAVSSASLPGSG LPSVGSIRPPHGLLKSPSAAAAAPL GGGGGGSGASGGFQHWGGMPCPCSM CQVPPPHHHVSAMGAGSLPRLTSDA K
Purity : >90% by SDS-PAGE.
Storage : Keep at -80°C for long term storage. Product is stable at 4 °C for at least 30 days.
Gene Name : OLIG2 oligodendrocyte lineage transcription factor 2 [ Homo sapiens ]
Official Symbol : OLIG2
Synonyms : OLIG2; protein kinase C-binding protein 2; basic domain, helix-loop-helix protein, class B, 1; BHLHB1; OLIGO2; RACK17; PRKCBP2; bHLHe19;
Gene ID : 10215
mRNA Refseq : NM_005806
Protein Refseq : NP_005797
MIM :
UniProt ID :
Function : DNA binding; HMG box domain binding; protein homodimerization activity; sequence-specific DNA binding transcription factor activity; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does OLIG2 (Oligodendrocyte Transcription Factor 2) regulate the development and maturation of oligodendrocytes? 09/23/2022

OLIG2 is essential for the development and maturation of oligodendrocytes, which form myelin in the nervous system.

What is the impact of OLIG2 on the pathogenesis of gliomas and other brain tumors? 02/03/2021

OLIG2 is implicated in the development of gliomas, influencing tumor cell differentiation and growth.

What role does OLIG2 play in neural stem cell differentiation, particularly in the central nervous system? 06/05/2020

OLIG2 plays a crucial role in directing neural stem cells to differentiate into oligodendrocytes and neurons in the CNS.

How does OLIG2 influence neuronal and glial cell interactions during brain development? 12/11/2019

OLIG2 affects interactions between neurons and glial cells, essential for proper brain development.

How do alterations in OLIG2 expression or function affect neurodevelopmental disorders? 06/05/2019

Changes in OLIG2 can lead to neurodevelopmental disorders due to altered brain cell development and function.

How does OLIG2 contribute to the repair and regeneration of myelin in demyelinating diseases? 04/21/2018

OLIG2 contributes to myelin repair and regeneration, crucial in demyelinating diseases like multiple sclerosis.

What are the mechanisms by which OLIG2 modulates gene expression in neurodevelopmental processes? 01/09/2018

OLIG2 modulates gene expression, guiding key neurodevelopmental processes and cell fate decisions.

Customer Reviews (3)

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Reviews
01/24/2019

    Swift protein sequencing, invaluable for protein identification.

    07/05/2018

      Consistent western blot results, a lab necessity for us.

      05/26/2018

        Great protein crystallization service, vital for structural biology studies.

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