Recombinant Human OLR1 Protein, MYC/DDK-tagged

• Cat.No.: OLR1-296H
• Product Overview: Recombinant human OLR1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 30.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: oxidized low density lipoprotein receptor 1 [ Homo sapiens ]
• Official Symbol: OLR1
• Synonyms: CLEC8A; LOX1; LOXIN; SCARE1; SLOX1
• Gene ID: 4973
• mRNA Refseq: NM_001172632.1
• Protein Refseq: NP_001166103.1
• MIM: 602601
• UniProt ID: P78380