Recombinant Human P4HB, MYC/DDK-tagged
Cat.No. : | P4HB-116H |
Product Overview : | Recombinant Human P4HB fused with C-terminal MYC/DDK, was expressed in HEK293 Cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Molecular Mass : | 55.2 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | P4HB prolyl 4-hydroxylase, beta polypeptide [ Homo sapiens (human) ] |
Official Symbol : | P4HB |
Synonyms : | P4HB; DSI; GIT; PDI; PHDB; PDIA1; PO4DB; PO4HB; PROHB; ERBA2L; P4Hbeta; prolyl 4-hydroxylase, beta polypeptide; protein disulfide-isomerase; p55; protocollagen hydroxylase; prolyl 4-hydroxylase subunit beta; collagen prolyl 4-hydroxylase beta; thyroid hormone-binding protein p55; glutathione-insulin transhydrogenase; cellular thyroid hormone-binding protein; protein disulfide isomerase-associated 1; protein disulfide isomerase/oxidoreductase; protein disulfide isomerase family A, member 1; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; EC 5.3.4.1 |
Gene ID : | 5034 |
mRNA Refseq : | NM_000918 |
Protein Refseq : | NP_000909 |
MIM : | 176790 |
UniProt ID : | P07237 |
Chromosome Location : | 17q25 |
Pathway : | Chylomicron-mediated lipid transport; Collagen biosynthesis and modifying enzymes; Collagen formation |
Function : | electron carrier activity; procollagen-proline 4-dioxygenase activity; protein binding |
Products Types
◆ Recombinant Protein | ||
P4HB-2042C | Recombinant Cricetulus Griseus P4HB Protein (20-509 aa), His-tagged | +Inquiry |
P4HB-1478H | Recombinant Human P4HB Protein (18-508 aa), His-tagged | +Inquiry |
P4hb-4642M | Recombinant Mouse P4hb Protein, Myc/DDK-tagged | +Inquiry |
P4HB-3904R | Recombinant Rat P4HB Protein, His (Fc)-Avi-tagged | +Inquiry |
P4HB-27008TH | Recombinant Human P4HB, His-tagged | +Inquiry |
◆ Lysates | ||
P4HB-2764HCL | Recombinant Human P4HB cell lysate | +Inquiry |
P4HB-2121MCL | Recombinant Mouse P4HB cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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