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Recombinant Human PAOX Protein, MYC/DDK-tagged

Cat.No. : PAOX-251H
Product Overview : Recombinant human PAOX protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
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Description : Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. [UniProtKB/Swiss-Prot Function]
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 34.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : polyamine oxidase [ Homo sapiens ]
Official Symbol : PAOX
Synonyms : PAO; PAO
Gene ID : 196743
mRNA Refseq : NM_152911.2
Protein Refseq : NP_690875.1
UniProt ID : Q6QHF9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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