Recombinant Human PDCD1 Protein, Fc/His-tagged, Alexa Fluor 647 conjugated
Cat.No. : | PDCD1-3244HAF647 |
Product Overview : | Alexa Fluor 647 conjugated recombinant human PDCD1 extracellular domain (Met 1-Gln 167) (NP_005009.2), fused with the polyhistidine-tagged Fc region of human IgG1 at the C-terminus, was produced in Human Cell. |
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Source : | HEK293 |
Species : | Human |
Tag : | Fc/His |
Form : | Lyophilized |
Molecular Mass : | The recombinant human PD1/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 390 amino acids and has a calculated molecular mass of 44 kDa. As a result of glycosylation, rhPD1/Fc monomer migrates as an approximately 60-65 kDa protein in SDS-PAGE under reducing conditions. |
Protein length : | 390 |
Endotoxin : | < 1.0 EU/ μg of the protein as determined by the LAL method. |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 647 via amines Excitation = 650 nm Emission = 668 nm |
Stability : | Samples are stable for up to 12 months from date of receipt at -70 centigrade. |
Storage : | Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from sterile PBS, pH 7.4 |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | PDCD1 programmed cell death 1 [ Homo sapiens ] |
Official Symbol : | PDCD1 |
Gene ID : | 5133 |
mRNA Refseq : | NM_005018 |
Protein Refseq : | NP_005009 |
MIM : | 600244 |
UniProt ID : | Q15116 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (14)
Ask a questionPDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.
PDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.
PDCD1 helps develop immune tolerance, preventing overactive immune responses.
PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.
PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.
PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.
PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.
PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.
PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.
PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.
PDCD1 helps develop immune tolerance, preventing overactive immune responses.
Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.
PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.
Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.
Customer Reviews (3)
Write a reviewTimely antibody validation, a valuable asset for our laboratory.
Precise protein quantification, fundamental for maintaining data accuracy.
Dependable peptide synthesis, accelerates our peptide-based projects effectively.
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