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Recombinant Human PLAUR Protein, MYC/DDK-tagged

Cat.No. : PLAUR-1866H
Product Overview : Recombinant human PLAUR protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
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Description : This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 34.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PLAUR plasminogen activator, urokinase receptor [ Homo sapiens ]
Official Symbol : PLAUR
Synonyms : CD87; U-PAR; UPAR; URKR
Gene ID : 5329
mRNA Refseq : NM_001005376
Protein Refseq : NP_001005376
MIM : 173391
UniProt ID : Q03405

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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