Recombinant Human PLEKHA1 Protein, MYC/DDK-tagged

• Cat.No.: PLEKHA1-2108H
• Product Overview: Recombinant human PLEKHA1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Description: This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 45.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 [ Homo sapiens ]
• Official Symbol: PLEKHA1
• Synonyms: TAPP1; TAPP1
• Gene ID: 59338
• mRNA Refseq: NM_001001974
• Protein Refseq: NP_001001974
• MIM: 607772
• UniProt ID: Q9HB21