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Recombinant Human PODXL Protein, DDK/HIS-tagged

Cat.No. : PODXL-063H
Product Overview : Recombinant Human PODXL(Gln32 - Pro461) fused with His/DDK tag at N-terminal was expressed in HEK293.
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  • Gene Information
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Description : This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
Source : HEK293 cells
Tag : DDK/HIS
Form : DPBS, 10% glycerol
Molecular Mass : 47.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PODXL podocalyxin-like [ Homo sapiens ]
Official Symbol : PODXL
Synonyms : PODXL; podocalyxin-like; podocalyxin; Gp200; PC; PCLP; GCTM-2 antigen; podocalyxin-like protein 1; PCLP-1; MGC138240;
Gene ID : 5420
mRNA Refseq : NM_001018111
Protein Refseq : NP_001018121
MIM : 602632
UniProt ID : O00592

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does PODXL contribute to cancer metastasis? 02/09/2022

PODXL promotes cancer cell migration and invasion, facilitating the spread of cancer to distant organs and tissues.

Can PODXL be detected in circulating tumor cells (CTCs)? 07/26/2021

Yes, PODXL expression in CTCs can be a valuable biomarker for monitoring cancer progression and treatment response.

Are there ongoing clinical trials targeting PODXL in cancer therapy? 02/17/2021

Yes, several clinical trials are investigating the efficacy of drugs targeting PODXL as a novel approach in cancer treatment.

Are there therapeutic implications for targeting PODXL in cancer treatment? 03/22/2019

Yes, targeting PODXL is being explored as a potential therapeutic strategy to inhibit cancer progression and metastasis.

Can PODXL be used for prognosis in cancer patients? 04/03/2016

Elevated PODXL expression is often associated with poor prognosis in cancer patients, indicating a more aggressive disease course.

Customer Reviews (3)

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Reviews
03/22/2023

    Manufacturers may offer the option for custom protein production.

    02/26/2023

      They can assist in identifying the most suitable experimental protocols or provide recommendations for optimal usage.

      07/24/2017

        Manufacturers can provide researchers with purified and validated ARL5B protein, ensuring its quality and reliability for use in experiments and trials.

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