Recombinant Human POLH Protein, MYC/DDK-tagged
Cat.No. : | POLH-2456H |
Product Overview : | Recombinant Human POLH protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 78.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | POLH polymerase (DNA directed), eta [ Homo sapiens ] |
Official Symbol : | POLH |
Synonyms : | RAD30; RAD30A; XP-V; XPV |
Gene ID : | 5429 |
mRNA Refseq : | NM_006502 |
Protein Refseq : | NP_006493 |
MIM : | 603968 |
UniProt ID : | Q9Y253 |
Products Types
◆ Recombinant Protein | ||
Polh-4989M | Recombinant Mouse Polh Protein, Myc/DDK-tagged | +Inquiry |
POLH-1730H | Recombinant Human POLH Protein, His (Fc)-Avi-tagged | +Inquiry |
POLH-6910M | Recombinant Mouse POLH Protein, His (Fc)-Avi-tagged | +Inquiry |
POLH-1523H | Recombinant Human POLH protein | +Inquiry |
POLH-3733Z | Recombinant Zebrafish POLH | +Inquiry |
◆ Lysates | ||
POLH-1392HCL | Recombinant Human POLH cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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