Recombinant Human PPP1R14A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PPP1R14A-4998H
• Product Overview: PPP1R14A MS Standard C13 and N15-labeled recombinant protein (NP_150281) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 16.7 kDa
• AA Sequence: MAAQRLGKRVLSKLQSPSRARGPGG SPGGLQKRHARVTVKYDRRELQRRL DVEKWIDGRLEELYRGMEADMPDEI NIDELLELESEEERSRKIQGLLKSC GKPVEDFIQELLAKLQGLHRQPGLR QPSPSHDGSLSPLQDRARTAHPTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PPP1R14A protein phosphatase 1 regulatory inhibitor subunit 14A [ Homo sapiens (human) ]
• Official Symbol: PPP1R14A
• Synonyms: PPP1R14A; protein phosphatase 1, regulatory (inhibitor) subunit 14A; PPP1INL; protein phosphatase 1 regulatory subunit 14A; 17 kDa PKC potentiated inhibitory protein of PP1; 17 KDa protein; CPI 17; PKC potentiated inhibitory protein of PP1; 17-KDa protein; PKC-potentiated inhibitory protein of PP1; 17 kDa PKC-potentiated inhibitory protein of PP1; 17-kDa PKC-potentiated inhibitory protein of PP1; protein kinase C-potentiated inhibitor protein of 17 kDa; CPI17; CPI-17
• Gene ID: 94274
• mRNA Refseq: NM_033256
• Protein Refseq: NP_150281
• MIM: 608153
• UniProt ID: Q96A00