Recombinant Human PPP1R1B Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PPP1R1B-5421H
• Product Overview: PPP1R1B MS Standard C13 and N15-labeled recombinant protein (NP_115568) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 22.8 kDa
• AA Sequence: MDPKDRKKIQFSVPAPPSQLDPRQV EMIRRRRPTPAMLFRLSEHSSPEEE ASPHQRASGEGHHLKSKRPNPCAYT PPSLKAVQRIAESHLQSISNLNENQ ASEEEDELGELRELGYPREEDEEEE EDDEEEEEEEDSQAEVLKVIRQSAG QKTTCGQGLEGPWERPPPLDESERD GGSEDQVEDPALSEPGEEPQRPSPS EPGTTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PPP1R1B protein phosphatase 1 regulatory inhibitor subunit 1B [ Homo sapiens (human) ]
• Official Symbol: PPP1R1B
• Synonyms: PPP1R1B; protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32); DARPP 32; dopamine and cAMP regulated phosphoprotein; FLJ20940; DARPP-32
• Gene ID: 84152
• mRNA Refseq: NM_032192
• Protein Refseq: NP_115568
• MIM: 604399
• UniProt ID: Q9UD71