Recombinant Human PPP2R1A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PPP2R1A-5688H
• Product Overview: PPP2R1A MS Standard C13 and N15-labeled recombinant protein (NP_055040) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 65.3 kDa
• AA Sequence: MAAADGDDSLYPIAVLIDELRNEDV QLRLNSIKKLSTIALALGVERTRSE LLPFLTDTIYDEDEVLLALAEQLGT FTTLVGGPEYVHCLLPPLESLATVE ETVVRDKAVESLRAISHEHSPSDLE AHFVPLVKRLAGGDWFTSRTSACGL FSVCYPRVSSAVKAELRQYFRNLCS DDTPMVRRAAASKLGEFAKVLELDN VKSEIIPMFSNLASDEQDSVRLLAV EACVNIAQLLPQEDLEALVMPTLRQ AAEDKSWRVRYMVADKFTELQKAVG PEITKTDLVPAFQNLMKDCEAEVRA AASHKVKEFCENLSADCRENVIMSQ ILPCIKELVSDANQHVKSALASVIM GLSPILGKDNTIEHLLPLFLAQLKD ECPEVRLNIISNLDCVNEVIGIRQL SQSLLPAIVELAEDAKWRVRLAIIE YMPLLAGQLGVEFFDEKLNSLCMAW LVDHVYAIREAATSNLKKLVEKFGK EWAHATIIPKVLAMSGDPNYLHRMT TLFCINVLSEVCGQDITTKHMLPTV LRMAGDPVANVRFNVAKSLQKIGPI LDNSTLQSEVKPILEKLTQDQDVDV KYFAQEALTVLSLATRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PPP2R1A protein phosphatase 2 scaffold subunit Aalpha [ Homo sapiens (human) ]
• Official Symbol: PPP2R1A
• Synonyms: PPP2R1A; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform, protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; PP2A Aalpha; PR65A; protein phosphatase 2; 65kDa regulatory subunit A; protein phosphatase 2A; regulatory subunit A; alpha isoform; PP2A subunit A isoform R1-alpha; PP2A subunit A isoform PR65-alpha; medium tumor antigen-associated 61 KDA protein; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform; PP2AAALPHA; MGC786; PP2A-Aalpha
• Gene ID: 5518
• mRNA Refseq: NM_014225
• Protein Refseq: NP_055040
• MIM: 605983
• UniProt ID: P30153