Recombinant Human PRC1 Protein, MYC/DDK-tagged

• Cat.No.: PRC1-2915H
• Product Overview: Recombinant Human PRC1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 71.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PRC1 protein regulator of cytokinesis 1 [ Homo sapiens ]
• Official Symbol: PRC1
• Synonyms: ASE1; ASE1
• Gene ID: 9055
• mRNA Refseq: NM_003981
• Protein Refseq: NP_003972
• MIM: 603484
• UniProt ID: O43663