"PRKAB2" Related Products

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Recombinant Human PRKAB2 protein, His/MBP-tagged

Cat.No.: PRKAB2-369H
Product Overview: Recombinant Human PRKAB2(1-112 aa aa) fused with His/MBP tag was expressed in E. coli.
Description: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
Source: E. coli
Species: Human
Tag : His/MBP
Form: Liquid in PBS
Protein length: 1-112 aa
Purity: SDS-PAGE >90%
Applications: WB Positive Control
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name: PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit [ Homo sapiens ]
Official Symbol: PRKAB2
Synonyms: PRKAB2; protein kinase, AMP-activated, beta 2 non-catalytic subunit; 5-AMP-activated protein kinase subunit beta-2; AMPK beta 2; AMPK beta-2 chain; AMPK subunit beta-2; 5-AMP-activated protein kinase, beta-2 subunit; MGC61468;
Gene ID: 5565
mRNA Refseq: NM_005399
Protein Refseq: NP_005390
MIM: 602741
UniProt ID: O43741

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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