|Product Overview:||Recombinant Human PROC(Met1-Pro461) fused with His tag at C-terminal was expressed in NS0.|
|Predicted N Terminal:||Ala43 (mature and light chains) & Asp200 (heavy chain)|
|Form:||Lyophilized from a 0.2 μm filtered solution in Sodium Acetate and NaCl.|
|Bio-activity:||Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. The specific activity is >25 pmol/min/µg.|
|Molecular Mass:||Predicted Molecular Mass: 49 (mature), 31 (heavy), 18 (light) kDa;
SDS-PAGE: 60-64 kDa, 41-44 kDa and 22 kDa, reducing conditions.
|Endotoxin:||<1.0 EU per 1 μg of the protein by the LAL method.|
|Purity:||>95%, by SDS-PAGE under reducing conditions and visualized by silver stain|
|Storage:||Avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
|Reconstitution:||Reconstitute at 200 μg/mL in sterile, deionized water.|
|Gene Name:||PROC protein C (inactivator of coagulation factors Va and VIIIa) [ Homo sapiens ]|
|Synonyms:||PROC; protein C (inactivator of coagulation factors Va and VIIIa); vitamin K-dependent protein C; autoprothrombin IIA; anticoagulant protein C; blood coagulation factor XIV; PC; APC; PROC1; THPH3; THPH4;|
|Pathway:||Cell surface interactions at the vascular wall, organism-specific biosystem; Common Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Gamma-carboxylation of protein precursors, organism-specific biosystem;|