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Active Recombinant Human PSPN Protein

Cat.No. : PSPN-098H
Product Overview : The mature recombinant human Persephin protein consists of 96 amino acids (61-156) without tag was expressed in E. coli.
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  • Gene Information
  • Related Products
Description : This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma.
Source : E. coli
Species : Human
Bio-activity : Measured in a cell proliferation assay using TT human medullary thyroid cancer cells. The ED50 for this effect is 4-16 ng/mL.
Molecular Mass : 20.5 kDa
Product-Related Proteins : 61-156
Endotoxin : < 0.1 EU/μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : At -80 centigrade. Avoid repeated freeze-thaw cycles.
Storage Buffer : PBS
Gene Name : PSPN persephin [ Homo sapiens (human) ]
Official Symbol : PSPN
Synonyms : PSPN; persephin; PSP; persephin
Gene ID : 5623
mRNA Refseq : NM_004158
Protein Refseq : NP_004149
MIM : 602921
UniProt ID : O60542

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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