| Description : |
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
36.6 kDa |
| AA Sequence : |
MAEGERQPPPDSSEEAPPATQNFII PKKEIHTVPDMGKWKRSQAYADYIG FILTLNEGVKGKKLTFEYRVSEAIE KLVALLNTLDRWIDETPPVDQPSRF GNKAYRTWYAKLDEEAENLVATVVP THLAAAVPEVAVYLKESVGNSTRID YGTGHEAAFAAFLCCLCKIGVLRVD DQIAIVFKVFNRYLEVMRKLQKTYR MEPAGSQGVWGLDDFQFLPFIWGSS QLIDHPYLEPRHFVDEKAVNENHKD YMFLECILFITEMKTGPFAEHSNQL WNISAVPSWSKVNQGLIRMYKAECL EKFPVIQHFKFGSLLPIHPVTSGTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
