Recombinant Human PTPN2 Protein, His/GST-tagged PTPN2-05H

Recombinant Human PTPN2 Protein, His/GST-tagged


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Recombinant Human PTPN2 Protein, His/GST-tagged

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Cat.No. : PTPN2-05H
Product Overview : Recombinant human PDE1B protein (1-537) with a N-teminus His/GST-tag was expressed in insect cells.
Description : The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.
Source : Insect cell
Species : Human
Tag : His/GST
Form : Lyophilized from sterile PBS, pH 7.4
Molecular Mass : 22.3 kDa
Protein length : 25-222
Endotoxin : <1.0 EU/μg of the protein as determined by the LAL method
Purity : ≥75 % as determined by SDS-PAGE
Applications : Enzyme Activity, WB
Stability : ≥ 1 year
Storage : Store at -80 centigrade
SDS-PAGE Analysis of TCPTP :

Lane 1: MW Markers, Lane 2: TCPTP. SDS-PAGE Analysis of TCPTP. This protein has a calculated molecular weight of 64.4 kDa. It has an apparent molecular weight of approximately 60 kDa by SDS-PAGE under reducing condions.

Gene Name : PTPN2 protein tyrosine phosphatase non-receptor type 2 [ Homo sapiens (human) ]
Official Symbol : PTPN2
Synonyms : PTPN2; PTN2; PTPT; TCPTP; TC-PTP; TCELLPTP; tyrosine-protein phosphatase non-receptor type 2; T-cell protein tyrosine phosphatase
Gene ID : 5771
mRNA Refseq : NM_001207013
Protein Refseq : NP_001193942
MIM : 176887
UniProt ID : P17706

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